Alcet 5 mg - 10's Strip Tablet

Summary:

Indications of Alcet 5 mg

Levocetirizine is indicated in the treatment of symptoms associated with allergic conditions such as- perennial allergic rhinitis seasonal allergic rhinitis chronic idiopathic urticaria.

Theropeutic Class

Non-sedating antihistamines

Pharmacology

Alcet 5 mg is a preparation of Alcet 5 mg. Levocetirizine is the active (levo) isomer of Cetirizine. It is a new highly effective and well-tolerated non-sedating antihistamine with potent antiallergic properties.

It has a two-fold higher affinity for H1-receptors than Cetirizine.

Levocetirizine has a rapid and long-lasting action, allowing once-a-day administration.

Dosage and Administration of Alcet 5 mg

Adults and children 12 years of age and older: 5 mg once daily in the eveningChildren 6 to 11 years of age: 2.5 mg once daily in the eveningChildren 6 months to 5 years of age: 1.25 mg (1/2 teaspoon oral solution) once daily in the evening.

Renal Impairment: Adjust the dose in patients 12 years of age and older with decreased renal function.

Dosage of Alcet 5 mg

Adult and children 12 years of age and older: The recommended dose is 5 mg once daily.Children 6 to 11 years of age: The recommended dose is 2.5 mg (½ tablet or 1 teaspoon oral solution) once daily.

Children 6 months to 5 years of age: The recommended dose is 1.25 mg (½ teaspoon oral solution) once daily.

Pediatric use: The recommended dose for the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria in patients 6 months to 17 years of age is based on extrapolation of efficacy from adults 18 years of age and older.

Geriatric use: In clinical studies, each approved indication did not include sufficient numbers of patients aged 65 years and older to determine whether they respond differently than younger patients.

Hepatic impairment: No dosage adjustment is required in patients with solely hepatic impairment.

Renal impairment: Mild renal impairment (creatinine clearance: 50-80 ml/min): a dose of 2.5 mg once daily is recommended. Moderate renal impairment (creatinine clearance: 30-50 ml/min): a dose of 2.5 mg once every other day is recommended.

Severe renal impairment (creatinine clearance: 10-30 ml/min): a dose of 2.5 mg twice weekly (administered once every 3-4 days) is recommended.

End-stage renal disease patients (creatinine clearance: